Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.57 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.57 |
| ▸ | CCR6 | P51684 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855140 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDHTTCACNA1B | |
| SCHEMBL2845355 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1MAPTHPGDHTTCACNA1B | |
| SCHEMBL2846340 | 0.76 | TYK2 (0.42) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL2006114 | 0.74 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDHTTCACNA1B | |
| SCHEMBL4407371 | 0.74 | ALDH1A1 (0.79) | ALDH1A1MAPTHPGDHTTCACNA1B | |
| SCHEMBL9112952 | 0.71 | SMN1; SMN2 (0.52) | ALDH1A1HTTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL4408152 | 0.71 | ALDH1A1 (0.74) | ALDH1A1MAPTHPGDHTTCACNA1B | |
| SCHEMBL13354144 | 0.69 | MAPK13 (0.49) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL10977161 | 0.69 | ALDH1A1 (0.70) | ALDH1A1MAPTHPGDHTTCACNA1B | |
| SCHEMBL2850071 | 0.69 | MEN1 (0.47) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130509-A1 | NOVEL ANTIBIOTICS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWE- TENSCHAPPELIJK ONDERZOEK TNO (NL) | 2010-05-27 | — | — | US | claimed |
| EP-1978021-A1 | Novel antibiotics | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2008-10-08 | — | — | EP | claimed |
| US-20100130509-A1 | NOVEL ANTIBIOTICS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWE- TENSCHAPPELIJK ONDERZOEK TNO (NL) | 2010-05-27 | — | — | US | disclosed |
| US-20100130509-A1 | NOVEL ANTIBIOTICS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWE- TENSCHAPPELIJK ONDERZOEK TNO (NL) | 2010-05-27 | — | — | US | disclosed |
| US-20100130509-A1 | NOVEL ANTIBIOTICS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWE- TENSCHAPPELIJK ONDERZOEK TNO (NL) | 2010-05-27 | — | — | US | disclosed |
| EP-2139872-A1 | NOVEL ANTIBIOTICS | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008120992-A1 | NOVEL ANTIBIOTICS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2008-10-09 | — | — | WO | disclosed |
| EP-1978021-A1 | Novel antibiotics | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2008-10-08 | — | — | EP | disclosed |
| EP-1978021-A1 | Novel antibiotics | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2008-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130509-A1 | NOVEL ANTIBIOTICS | TMEM165, LAS1L, RPS2 | ALDH1A1 4431/4885MAPT 2857/4885HPGD 4498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.