SCHEMBL4408152

SCHEMBL4408152

ClC(Cl)(Cl)C(Cl)(Cl)c1nnnn1-c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 15/20 0.74
HTT P42858 4/20 0.74
HPGD P15428 3/20 0.74
MAPT P10636 3/20 0.74
CACNA1B Q00975 2/20 0.74
APBA1 Q02410 2/20 0.74
CCR6 P51684 1/20 0.74
HSP90AA1 P07900 1/20 0.51
NPSR1 Q6W5P4 3/20 0.45
TSHR P16473 3/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
LMNA P02545 3/20 0.42
HSD17B10 Q99714 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PKM P14618 1/20 0.41
NLRP3 Q96P20 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4407371 0.85 ALDH1A1 (0.79) ALDH1A1HTTHPGDMAPTCACNA1B
SCHEMBL2006114 0.85 ALDH1A1 (1.00) ALDH1A1HTTHPGDMAPTCACNA1B
SCHEMBL10977161 0.79 ALDH1A1 (0.70) ALDH1A1HTTHPGDMAPTCACNA1B
SCHEMBL4408113 0.78 ALDH1A1 (0.68) ALDH1A1HTTHPGDMAPTCACNA1B
SCHEMBL4407904 0.78 ALDH1A1 (0.68) ALDH1A1HTTHPGDMAPTCACNA1B
SCHEMBL4405847 0.75 ALDH1A1 (0.64) ALDH1A1HTTHPGDMAPTCACNA1B
SCHEMBL4405642 0.72 LMNA (0.51) ALDH1A1HTTHPGDMAPTCACNA1B
SCHEMBL2002688 0.72 ALDH1A1 (0.73) ALDH1A1HTTHPGDMAPTCACNA1B
SCHEMBL2853837 0.71 ALDH1A1 (0.57) ALDH1A1HTTHPGDMAPTCACNA1B
SCHEMBL10600988 0.71 ALDH1A1 (0.58) ALDH1A1HTTHPGDMAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859782-B1 Composition for coloring and/or lightening human hair comprising tetrazoles HENKEL AG & CO KGAA (DE) 2009-12-30 EP disclosed
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed