Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980817 | 0.79 | HTR7 (0.50) | KDRUSP30HTR7LMNAMAPT | |
| SCHEMBL2406268 | 0.77 | HDAC1 (0.40) | KDRUSP30HTR7HSD17B1HSD17B2 | |
| SCHEMBL17107113 | 0.74 | RAB9A (0.52) | USP30HSD17B1HSD17B2NPC1LMNA | |
| SCHEMBL899508 | 0.73 | HDAC1 (0.47) | KDRHTR7NPC1LMNAMAPT | |
| SCHEMBL28743533 | 0.72 | NPC1 (0.57) | KDRHSD17B1HSD17B2NPC1LMNA | |
| SCHEMBL22988620 | 0.72 | HTR7 (0.44) | KDRUSP30HTR7HSD17B1HSD17B2 | |
| SCHEMBL2410374 | 0.72 | HSD17B1 (0.56) | KDRUSP30HTR7HSD17B1HSD17B2 | |
| SCHEMBL12249808 | 0.70 | ALDH1A1 (0.48) | NPC1LMNAMAPTHPGDRAB9A | |
| SCHEMBL146522 | 0.69 | KDR (0.52) | KDRHTR7 | |
| SCHEMBL3050460 | 0.68 | TSHR (0.55) | LMNAMAPTHPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321526-A | Method for synthesizing heteroaromatic methylamine compound through redox-decarboxylation coupling reaction | 西北师范大学 | 2021-02-05 | — | — | CN | disclosed |