Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861261 | 0.90 | HPGD (0.64) | HPGDALDH1A1RAB9ANPC1POLB | |
| SCHEMBL2854225 | 0.86 | CCR1 (0.60) | HPGDMAPTCCR1 | |
| SCHEMBL2863421 | 0.86 | EPHX1 (0.46) | HPGDEPHX1ALDH1A1RAB9AAOC3 | |
| SCHEMBL2856304 | 0.85 | KEAP1 (0.53) | HPGDEPHX1ALDH1A1AOC3POLB | |
| SCHEMBL2858313 | 0.84 | P2RX7 (0.56) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2859509 | 0.84 | KMT2A (0.54) | HPGDEPHX1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2852334 | 0.83 | HPGD (0.55) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2853344 | 0.83 | HPGD (0.55) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2853267 | 0.83 | HPGD (0.55) | HPGDALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2860234 | 0.82 | HPGD (0.54) | HPGDALDH1A1RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |