Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853344 | 0.96 | HPGD (0.55) | HPGDMAPTALDH1A1RAB9ALMNA | |
| SCHEMBL2863134 | 0.94 | CCR1 (0.48) | HPGDMAPTALDH1A1SMN1; SMN2P2RX7 | |
| SCHEMBL2861261 | 0.92 | HPGD (0.64) | HPGDMAPTALDH1A1RAB9ALMNA | |
| SCHEMBL2857180 | 0.89 | NPSR1 (0.53) | MAPTRAB9AP2RX7SMOCCR1 | |
| SCHEMBL2852334 | 0.89 | HPGD (0.55) | HPGDMAPTALDH1A1RAB9ALMNA | |
| SCHEMBL2854802 | 0.88 | LMNA (0.48) | MAPTALDH1A1LMNACCR1FAAH | |
| SCHEMBL2856499 | 0.85 | ALDH1A1 (0.53) | HPGDMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2854847 | 0.85 | ALDH1A1 (0.48) | HPGDMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2854625 | 0.85 | POLB (0.48) | HPGDALDH1A1RAB9ALMNAP2RX7 | |
| SCHEMBL2858157 | 0.84 | POLB (0.55) | HPGDALDH1A1RAB9ALMNAP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |