Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CCR1 | P32246 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853267 | 0.96 | HPGD (0.55) | HPGDCCR1MAPK1MAPTALDH1A1 | |
| SCHEMBL2863134 | 0.94 | CCR1 (0.48) | HPGDCCR1MAPK1MAPTALDH1A1 | |
| SCHEMBL2861261 | 0.92 | HPGD (0.64) | HPGDMAPK1MAPTALDH1A1RAB9A | |
| SCHEMBL2856499 | 0.89 | ALDH1A1 (0.53) | HPGDCCR1MAPTALDH1A1KMT2A | |
| SCHEMBL2857180 | 0.89 | NPSR1 (0.53) | CCR1MAPK1MAPTRAB9ASMO | |
| SCHEMBL2854802 | 0.88 | LMNA (0.48) | CCR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2860234 | 0.88 | HPGD (0.54) | HPGDMAPK1MAPTALDH1A1RAB9A | |
| SCHEMBL2854625 | 0.87 | POLB (0.48) | HPGDCCR1ALDH1A1RAB9ANPC1 | |
| SCHEMBL2850369 | 0.85 | P2RX7 (0.56) | CCR1MAPTTP53P2RX7 | |
| SCHEMBL2854804 | 0.85 | MAPK1 (0.48) | HPGDCCR1MAPK1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |