Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 4/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861261 | 0.92 | HPGD (0.64) | HPGDGAARAB9AMEN1NPC1 | |
| SCHEMBL2857180 | 0.89 | NPSR1 (0.53) | GAACCR1RAB9ATP53MAPT | |
| SCHEMBL2859872 | 0.89 | TAAR1 (0.54) | HPGDGAANR3C1RAB9AMEN1 | |
| SCHEMBL2853267 | 0.89 | HPGD (0.55) | HPGDCCR1RAB9ANPC1TP53 | |
| SCHEMBL2858313 | 0.88 | P2RX7 (0.56) | HPGDGAACCR1RAB9AMEN1 | |
| SCHEMBL2854531 | 0.88 | LMNA (0.52) | CCR1NR3C1RAB9AMEN1NPC1 | |
| SCHEMBL2858097 | 0.84 | P2RX7 (0.53) | HPGDRAB9ANPC1TP53MAPT | |
| SCHEMBL2853344 | 0.84 | HPGD (0.55) | HPGDCCR1RAB9AMEN1NPC1 | |
| SCHEMBL2856356 | 0.84 | ALDH1A1 (0.47) | HPGDGAACCR1NR3C1RAB9A | |
| SCHEMBL2860234 | 0.83 | HPGD (0.54) | HPGDGAANR3C1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |