Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 5/20 | 0.45 |
| ▸ | CNR2 | P34972 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852334 | 0.88 | HPGD (0.55) | SMN1; SMN2HPGDCCR1RAB9AMEN1 | |
| SCHEMBL2861261 | 0.87 | HPGD (0.64) | SMN1; SMN2HPGDRAB9AMEN1NPC1 | |
| SCHEMBL2859307 | 0.85 | TSHR (0.46) | P2RX7TSHRSMN1; SMN2PPARGNPSR1 | |
| SCHEMBL2854337 | 0.84 | HPGD (0.53) | SMN1; SMN2HPGDCCR1RAB9ANPC1 | |
| SCHEMBL2853267 | 0.84 | HPGD (0.55) | P2RX7SMN1; SMN2HPGDCCR1RAB9A | |
| SCHEMBL2858097 | 0.84 | P2RX7 (0.53) | P2RX7HPGDRAB9ANPC1LMNA | |
| SCHEMBL2848480 | 0.82 | ALDH1A1 (0.61) | TSHRSMN1; SMN2HPGDRAB9AMEN1 | |
| SCHEMBL2856450 | 0.82 | HPGD (0.74) | P2RX7SMN1; SMN2HPGDCCR1RAB9A | |
| SCHEMBL2859509 | 0.81 | KMT2A (0.54) | TSHRSMN1; SMN2HPGDKMT2AALDH1A1 | |
| SCHEMBL2854225 | 0.81 | CCR1 (0.60) | HPGDNPSR1CCR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |