Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.54 |
| ▸ | NPC1 | O15118 | 13/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848335 | 0.91 | ATM (0.54) | RAB9ANPC1MAPTHPGDPKM | |
| SCHEMBL2850131 | 0.90 | RAB9A (0.61) | RAB9ANPC1MAPTHPGDPKM | |
| SCHEMBL2852507 | 0.90 | NPC1 (0.51) | RAB9ANPC1MAPTHPGDPKM | |
| SCHEMBL2857953 | 0.89 | RAB9A (0.50) | RAB9ANPC1MAPTHPGDPKM | |
| SCHEMBL2853257 | 0.88 | MAPT (0.53) | RAB9ANPC1MAPTHPGDPKM | |
| SCHEMBL2857182 | 0.85 | RAB9A (0.48) | RAB9ANPC1MAPTHPGDPKM | |
| SCHEMBL2854815 | 0.84 | MEN1 (0.50) | RAB9ANPC1MAPTPKMSMN1; SMN2 | |
| SCHEMBL6204868 | 0.83 | MAPK1 (0.58) | RAB9ANPC1MAPTHPGDPKM | |
| SCHEMBL1195017 | 0.81 | MAPK1 (0.60) | RAB9ANPC1MAPTHPGDPKM | |
| SCHEMBL2856997 | 0.81 | ALDH1A1 (0.57) | RAB9AMAPTPKMMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |