Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854348 | 0.91 | RAB9A (0.54) | NPC1RAB9APKMHPGDNFKB1 | |
| SCHEMBL2852507 | 0.89 | NPC1 (0.51) | NPC1RAB9APKMHPGDNFKB1 | |
| SCHEMBL2853257 | 0.87 | MAPT (0.53) | NPC1RAB9APKMMEN1KMT2A | |
| SCHEMBL2852384 | 0.87 | NPC1 (0.54) | ATMNPC1RAB9APKMMEN1 | |
| SCHEMBL2857953 | 0.86 | RAB9A (0.50) | NPC1RAB9APKMHPGDNFKB1 | |
| SCHEMBL2854815 | 0.83 | MEN1 (0.50) | NPC1RAB9APKMMEN1KMT2A | |
| SCHEMBL2853491 | 0.83 | ALDH1A1 (0.55) | ATMRAB9APKMNR3C1MAPT | |
| SCHEMBL2860975 | 0.83 | MAPT (0.49) | ATMNPC1MEN1KMT2ANR3C1 | |
| SCHEMBL2852334 | 0.83 | HPGD (0.55) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL2850131 | 0.82 | RAB9A (0.61) | NPC1RAB9APKMKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |