Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852417 | 0.90 | MAPT (0.49) | MEN1KMT2ARAB9ANPC1PKM | |
| SCHEMBL2854348 | 0.84 | RAB9A (0.54) | RAB9ANPC1PKMMAPK1ALDH1A1 | |
| SCHEMBL2848335 | 0.83 | ATM (0.54) | MEN1KMT2ARAB9ANPC1PKM | |
| SCHEMBL2860824 | 0.83 | LMNA (0.57) | MEN1KMT2ARAB9APKMMAPK1 | |
| SCHEMBL2860786 | 0.83 | MAPT (0.49) | MEN1KMT2AKDM4ENR3C1ALDH1A1 | |
| SCHEMBL2857897 | 0.83 | MAPT (0.47) | MEN1KMT2ARAB9ANPC1PKM | |
| SCHEMBL2854465 | 0.82 | RAB9A (0.47) | RAB9ANPC1PKMMAPK1ALDH1A1 | |
| SCHEMBL2853257 | 0.81 | MAPT (0.53) | MEN1KMT2ARAB9ANPC1PKM | |
| SCHEMBL2858097 | 0.81 | P2RX7 (0.53) | RAB9ANPC1LMNAMAPT | |
| SCHEMBL2854574 | 0.80 | HSP90AA1 (0.51) | MEN1KMT2ARAB9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |