Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | AQP1 | P29972 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28544407 | 0.77 | MAOB (0.46) | TAAR1AQP1KDM1ARCOR1LOXL2 | |
| SCHEMBL4118593 | 0.76 | AQP1 (0.41) | TAAR1AQP1SLC6A4SLC6A3KDM1A | |
| SCHEMBL4634991 | 0.71 | HSD11B1 (0.41) | — | |
| SCHEMBL13075233 | 0.67 | TAAR1 (0.44) | TAAR1SLC6A4SLC6A3LMNA | |
| SCHEMBL18543775 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL30175029 | 0.65 | MAOA (0.47) | TAAR1KDM1AMAOBMAOAOPRL1 | |
| SCHEMBL5349239 | 0.64 | MAOB (0.61) | TAAR1SLC6A3KDM1ARCOR1LOXL2 | |
| Cyclopentanamine SCHEMBL7481942 | 0.64 | LOXL2 (0.64) | TAAR1LOXL2MAOBTRPA1LMNA | |
| SCHEMBL29218585 | 0.64 | MAOB (0.48) | SLC6A3KDM1ARCOR1MAOBMAOA | |
| SCHEMBL14409776 | 0.64 | EPHX2 (0.43) | LOXL2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487811-B1 | N-SULFONYLUREA APOPTOSIS PROMOTERS | ABBOTT LAB (US) | 2007-09-05 | — | — | EP | disclosed |