Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.47 |
| ▸ | NPC1 | O15118 | 11/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856979 | 0.91 | RAB9A (0.46) | RAB9ANPC1PKMP2RY1MAPT | |
| SCHEMBL2850763 | 0.87 | MAPT (0.48) | RAB9ANPC1P2RY1MAPTSMN1; SMN2 | |
| SCHEMBL2857472 | 0.85 | ALDH1A1 (0.50) | RAB9APKMP2RY1MAPTALDH1A1 | |
| SCHEMBL2854815 | 0.82 | MEN1 (0.50) | RAB9ANPC1PKMMAPTSMN1; SMN2 | |
| SCHEMBL2858606 | 0.80 | P2RY1 (0.47) | P2RY1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2854348 | 0.80 | RAB9A (0.54) | RAB9ANPC1PKMMAPTSMN1; SMN2 | |
| SCHEMBL2855775 | 0.79 | P2RY1 (0.44) | RAB9ANPC1P2RY1MAPTSMN1; SMN2 | |
| SCHEMBL2857897 | 0.79 | MAPT (0.47) | RAB9ANPC1PKMMAPTSMN1; SMN2 | |
| SCHEMBL2854695 | 0.78 | MAPT (0.50) | RAB9APKMP2RY1MAPTALDH1A1 | |
| SCHEMBL2856355 | 0.77 | RAB9A (0.52) | RAB9ANPC1PKMMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |