Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854465 | 0.91 | RAB9A (0.47) | RAB9ANPC1PKMMAPTSMN1; SMN2 | |
| SCHEMBL2852417 | 0.84 | MAPT (0.49) | RAB9ANPC1PKMMAPTSMN1; SMN2 | |
| SCHEMBL2858606 | 0.82 | P2RY1 (0.47) | MAPTSMN1; SMN2P2RY1KDM4EGAA | |
| SCHEMBL2859099 | 0.81 | NPC1 (0.50) | RAB9ANPC1PKMMAPTSMN1; SMN2 | |
| SCHEMBL2850131 | 0.81 | RAB9A (0.61) | RAB9ANPC1PKMMAPTSMN1; SMN2 | |
| SCHEMBL2850763 | 0.79 | MAPT (0.48) | RAB9ANPC1MAPTSMN1; SMN2P2RY1 | |
| SCHEMBL2860460 | 0.78 | MAPT (0.54) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL2855775 | 0.77 | P2RY1 (0.44) | RAB9ANPC1MAPTSMN1; SMN2P2RY1 | |
| SCHEMBL2857472 | 0.77 | ALDH1A1 (0.50) | RAB9APKMMAPTP2RY1MAPK14 | |
| SCHEMBL2853093 | 0.76 | NPC1 (0.52) | RAB9ANPC1PKMMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |