Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.34 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.34 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.34 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859504 | 0.94 | TAAR1 (0.43) | MAPTTAAR1CNR1LMNATRPV1 | |
| SCHEMBL2850252 | 0.87 | TRPV1 (0.40) | P2RX7CNR1LMNAGAATRPV1 | |
| SCHEMBL2857979 | 0.86 | TRPV1 (0.39) | TAAR1CNR1TRPV1KDM4E | |
| SCHEMBL2850556 | 0.86 | KDM4E (0.41) | MAPTCES2CNR1LMNAGAA | |
| SCHEMBL2863154 | 0.84 | MAPT (0.45) | MAPTP2RX7SPRTP53LMNA | |
| SCHEMBL2850857 | 0.84 | TP53 (0.46) | MAPTP2RX7TAAR1CNR1TP53 | |
| SCHEMBL2860458 | 0.84 | TP53 (0.46) | MAPTP2RX7TAAR1CNR1TP53 | |
| SCHEMBL2856562 | 0.84 | MAPT (0.48) | MAPTP2RX7TAAR1TP53LMNA | |
| SCHEMBL2853347 | 0.83 | TRPV1 (0.41) | MAPTTRPV1ALDH1A1MAPK14PTGER4 | |
| SCHEMBL2859714 | 0.83 | KDM4E (0.42) | MAPTSPRCES2CNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |