Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.33 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.33 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860303 | 0.89 | TRPV1 (0.39) | TRPV1MALT1LMNAGAAHPGD | |
| SCHEMBL2859504 | 0.88 | TAAR1 (0.43) | TRPV1LMNACNR1 | |
| SCHEMBL2854467 | 0.87 | MAPT (0.36) | TRPV1LMNAGAACNR1P2RX7 | |
| SCHEMBL2854705 | 0.86 | ALDH1A1 (0.46) | TRPV1KEAP1NFE2L2LMNAHPGD | |
| SCHEMBL2857979 | 0.86 | TRPV1 (0.39) | TRPV1CNR1SCN9ARXFP1KDM4E | |
| SCHEMBL2858618 | 0.85 | ALDH1A1 (0.41) | TRPV1LMNACNR1P2RX7KDM4E | |
| SCHEMBL2853186 | 0.85 | TRPV1 (0.41) | TRPV1MALT1LMNAGAAHPGD | |
| SCHEMBL2854496 | 0.85 | P2RX7 (0.47) | TRPV1P2RX7KDM4EALDH1A1 | |
| SCHEMBL2848315 | 0.82 | TRPV1 (0.54) | TRPV1P2RX7KDM4EALDH1A1DHODH | |
| SCHEMBL2853347 | 0.81 | TRPV1 (0.41) | TRPV1HPGDFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |