Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854467 | 0.94 | MAPT (0.36) | TAAR1CNR1MAPTLMNATRPV1 | |
| SCHEMBL2859594 | 0.88 | TAAR1 (0.45) | TAAR1CNR1TRPA1MAPTGPBAR1 | |
| SCHEMBL2850252 | 0.88 | TRPV1 (0.40) | CNR1LMNATRPV1 | |
| SCHEMBL2860669 | 0.86 | TAAR1 (0.46) | TAAR1CNR1MAPTHRH4HRH3 | |
| SCHEMBL2859861 | 0.85 | TAAR1 (0.51) | TAAR1CNR1MAPTLMNACYP1A2 | |
| SCHEMBL2857979 | 0.85 | TRPV1 (0.39) | TAAR1CNR1MEN1KMT2AHSD17B10 | |
| SCHEMBL2853336 | 0.85 | TAAR1 (0.45) | TAAR1CNR1TRPA1MAPTHRH4 | |
| SCHEMBL2853347 | 0.84 | TRPV1 (0.41) | MAPTCCR1TRPV1 | |
| SCHEMBL2855547 | 0.83 | TAAR1 (0.54) | TAAR1CNR1MAPTLMNACCR1 | |
| SCHEMBL2860458 | 0.83 | TP53 (0.46) | TAAR1CNR1MAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |