Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | CCR1 | P32246 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854533 | 0.93 | MEN1 (0.46) | MAPTNPSR1NPC1RAB9APLCG1 | |
| SCHEMBL2860522 | 0.92 | MAPT (0.48) | MAPTCCR1NPSR1NPC1RAB9A | |
| SCHEMBL2857550 | 0.90 | TMPRSS4 (0.45) | MAPTCCR1NPSR1NPC1RAB9A | |
| SCHEMBL2852820 | 0.89 | TMPRSS4 (0.45) | MAPTCCR1NPSR1NPC1RAB9A | |
| SCHEMBL2852552 | 0.87 | MEN1 (0.51) | MAPTNPSR1NPC1RAB9AALDH1A1 | |
| SCHEMBL2853065 | 0.85 | NR3C1 (0.46) | MAPTNPSR1NPC1RAB9AALDH1A1 | |
| SCHEMBL2852924 | 0.85 | SMN1; SMN2 (0.46) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2857582 | 0.84 | MAPT (0.42) | MAPTCCR1NPSR1NPC1RAB9A | |
| SCHEMBL2854221 | 0.84 | MAPT (0.51) | MAPTCCR1NPSR1ALDH1A1LMNA | |
| SCHEMBL2853465 | 0.84 | RAB9A (0.44) | MAPTCCR1NPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |