Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860131 | 0.93 | ALDH1A1 (0.46) | RXFP1KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL2854517 | 0.92 | MAPT (0.42) | P2RX7CCR1RXFP1KDM4EALDH1A1 | |
| SCHEMBL2848513 | 0.90 | P2RX7 (0.43) | P2RX7CCR1KDM4EALDH1A1MAPT | |
| SCHEMBL2857875 | 0.89 | P2RX7 (0.45) | P2RX7CCR1KDM4EALDH1A1MAPT | |
| SCHEMBL2853063 | 0.89 | P2RX7 (0.48) | P2RX7CCR1RXFP1KDM4EALDH1A1 | |
| SCHEMBL2854346 | 0.86 | MAPT (0.52) | P2RX7CCR1RXFP1KDM4EALDH1A1 | |
| SCHEMBL2863154 | 0.85 | MAPT (0.45) | P2RX7CCR1KDM4EALDH1A1MAPT | |
| SCHEMBL2854716 | 0.85 | MTNR1A (0.47) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2857936 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2856562 | 0.84 | MAPT (0.48) | P2RX7KDM4EALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |