Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856750 | 0.93 | P2RX7 (0.42) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2854517 | 0.92 | MAPT (0.42) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2857274 | 0.91 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2854716 | 0.89 | MTNR1A (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2857936 | 0.89 | KDM4E (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2856697 | 0.88 | KDM4E (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2861634 | 0.86 | RAB9A (0.44) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL2854509 | 0.86 | KDM4E (0.50) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2859644 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB | |
| SCHEMBL2859726 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |