Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30901638 | 0.78 | PIN1 (0.40) | KIF11DNMT1SLC1A5PIN1NPC1 | |
| Hydrochloric Acid SCHEMBL31184535 | 0.77 | PIN1 (0.40) | KIF11DNMT1SLC1A5PIN1NPC1 | |
| SCHEMBL8633545 | 0.76 | SLC7A5 (0.43) | KIF11LTA4HAAK1PIN1NPC1 | |
| SCHEMBL8329546 | 0.75 | LTA4H (0.52) | LTA4HAAK1PIN1 | |
| SCHEMBL8803290 | 0.74 | LTA4H (0.46) | LTA4HAAK1 | |
| SCHEMBL8801039 | 0.73 | LTA4H (0.39) | KIF11LTA4HAAK1PIN1NPC1 | |
| SCHEMBL8799610 | 0.73 | KIF11 (0.39) | KIF11LTA4HAAK1NPC1 | |
| SCHEMBL8633149 | 0.73 | CYP4F2 (0.36) | LTA4HAAK1 | |
| SCHEMBL8799063 | 0.73 | LTA4H (0.45) | LTA4H | |
| SCHEMBL28549357 | 0.72 | NPC1 (0.36) | AAK1SLC1A5PIN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349876-B | Substituted biphenyl compound and pharmaceutical composition thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-03-02 | — | — | CN | disclosed |