Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 7/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5428506 | 0.83 | ALDH1A1 (0.50) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8801034 | 0.77 | IDO1 (0.46) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8801044 | 0.77 | ALDH1A1 (0.40) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7445938 | 0.77 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8633545 | 0.76 | SLC7A5 (0.43) | LTA4HALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8329546 | 0.76 | LTA4H (0.52) | LTA4HALDH1A1MAPTSMN1; SMN2AAK1 | |
| SCHEMBL8803290 | 0.75 | LTA4H (0.46) | LTA4HALDH1A1SMN1; SMN2AAK1MMP8 | |
| SCHEMBL28545211 | 0.73 | KIF11 (0.40) | LTA4HNPC1RAB9AAAK1PIN1 | |
| SCHEMBL8799063 | 0.73 | LTA4H (0.45) | LTA4HSMN1; SMN2LMNAMMP8 | |
| SCHEMBL8633149 | 0.71 | CYP4F2 (0.36) | LTA4HAAK1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |