Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28779668 | 0.88 | HDAC3 (0.49) | HDAC8TRPV1 | |
| SCHEMBL28549970 | 0.86 | NPSR1 (0.58) | GPR139TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL28555031 | 0.84 | LMNA (0.51) | GPR139TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL28554992 | 0.83 | ALDH1A1 (0.48) | TAS1R3TAS1R1MEN1KMT2AALDH1A1 | |
| SCHEMBL28555760 | 0.83 | TAS1R3 (0.52) | HDAC8TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL28554643 | 0.82 | HPGD (0.54) | GPR139MEN1KMT2ALMNA | |
| SCHEMBL28554447 | 0.81 | CTSL (0.47) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28551104 | 0.80 | HDAC3 (0.48) | MEN1KMT2A | |
| SCHEMBL28566084 | 0.79 | LMNA (0.43) | TAS1R3TAS1R1TSHRALDH1A1MRGPRX4 | |
| SCHEMBL28550547 | 0.78 | TAS1R3 (0.44) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778333-B | Tetrahydrooxazolopyridino-azoxanone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-07-05 | — | — | CN | disclosed |
| CN-112724157-B | Dihydrooxazolo [5,4-d ] pyrrolo [1,2-a ] pyrimidin-9 (5H) -one derivatives and use thereof | 中国科学院新疆理化技术研究所 | 2022-04-19 | — | — | CN | disclosed |
| CN-112851692-B | Oxazolo [5,4-d ] pyrido [1,2-a ] pyrimidone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-04-08 | — | — | CN | disclosed |
| CN-112851692-A | Oxazolo [5,4-d ] pyrido [1,2-a ] pyrimidone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2021-05-28 | — | — | CN | disclosed |
| CN-112778333-A | Tetrahydrooxazolopyridino-azoxanone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2021-05-11 | — | — | CN | disclosed |
| CN-112724157-A | Dihydrooxazolo [5,4-d ] pyrrolo [1,2-a ] pyrimidin-9 (5H) -one derivatives and use thereof | 中国科学院新疆理化技术研究所 | 2021-04-30 | — | — | CN | disclosed |