Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28545233 | 0.88 | GPR139 (0.48) | TRPV1HDAC8 | |
| SCHEMBL28566084 | 0.87 | LMNA (0.43) | EPHX2PPARGPPARATRPV1 | |
| SCHEMBL28550888 | 0.84 | ALDH1A1 (0.48) | HDAC3HDAC1HDAC2 | |
| SCHEMBL28558833 | 0.83 | L3MBTL1 (0.44) | HDAC3HDAC1HDAC2EPHX2NR1H4 | |
| SCHEMBL28549384 | 0.83 | MAPT (0.45) | HDAC1HDAC6 | |
| SCHEMBL28559436 | 0.82 | HTT (0.51) | HDAC3HDAC1HDAC2EPHX2POLB | |
| SCHEMBL28554497 | 0.82 | HDAC3 (0.43) | HDAC3HDAC1HDAC2POLBHDAC10 | |
| SCHEMBL28554447 | 0.81 | CTSL (0.47) | — | |
| SCHEMBL28557766 | 0.80 | CTSB (0.52) | HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28550547 | 0.79 | TAS1R3 (0.44) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778333-B | Tetrahydrooxazolopyridino-azoxanone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-07-05 | — | — | CN | disclosed |
| CN-112724157-B | Dihydrooxazolo [5,4-d ] pyrrolo [1,2-a ] pyrimidin-9 (5H) -one derivatives and use thereof | 中国科学院新疆理化技术研究所 | 2022-04-19 | — | — | CN | disclosed |
| CN-112851692-B | Oxazolo [5,4-d ] pyrido [1,2-a ] pyrimidone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-04-08 | — | — | CN | disclosed |
| CN-112851692-A | Oxazolo [5,4-d ] pyrido [1,2-a ] pyrimidone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2021-05-28 | — | — | CN | disclosed |
| CN-112778333-A | Tetrahydrooxazolopyridino-azoxanone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2021-05-11 | — | — | CN | disclosed |
| CN-112724157-A | Dihydrooxazolo [5,4-d ] pyrrolo [1,2-a ] pyrimidin-9 (5H) -one derivatives and use thereof | 中国科学院新疆理化技术研究所 | 2021-04-30 | — | — | CN | disclosed |