Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861567 | 0.90 | MALT1 (0.41) | MEN1KMT2AMAPTL3MBTL1KDM4E | |
| SCHEMBL2862974 | 0.88 | KEAP1 (0.50) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL2856385 | 0.86 | CCR1 (0.44) | LMNAKEAP1NFE2L2CARM1RXFP1 | |
| SCHEMBL2854463 | 0.85 | CA12 (0.44) | MEN1KMT2AMAPTL3MBTL1KDM4E | |
| SCHEMBL2857337 | 0.85 | KMT2A (0.43) | MEN1KMT2AMAPTL3MBTL1KDM4E | |
| SCHEMBL2856588 | 0.85 | KEAP1 (0.42) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL2855716 | 0.85 | KEAP1 (0.46) | MAPTLMNAKEAP1NFE2L2CARM1 | |
| SCHEMBL2855798 | 0.85 | MAPT (0.45) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL2855496 | 0.85 | KDM4E (0.46) | MEN1KMT2AMAPTL3MBTL1KDM4E | |
| SCHEMBL2862993 | 0.84 | MEN1 (0.41) | MEN1KMT2AMAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |