Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 3/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850487 | 0.94 | HTT (0.48) | NTRK1ALDH1A1MAPK1HTTMEN1 | |
| SCHEMBL2860851 | 0.93 | CNR1 (0.46) | NTRK1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL2850723 | 0.88 | TAOK3 (0.47) | ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL2857348 | 0.83 | SPR (0.54) | NTRK1MAPK14ALDH1A1MAPK1MAPT | |
| SCHEMBL2860401 | 0.82 | MAPK13 (0.47) | NTRK1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL2852200 | 0.77 | SPR (0.51) | MAPK14ALDH1A1MAPK1MAPTPDE2A | |
| SCHEMBL2856997 | 0.76 | ALDH1A1 (0.57) | MAPK14ALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL2854219 | 0.76 | ALDH1A1 (0.47) | NTRK1ALDH1A1MAPK1MAPTHTT | |
| SCHEMBL5325459 | 0.76 | ALDH1A1 (0.53) | MAPK14ALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL2854556 | 0.75 | DRD4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |