Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859365 | 0.93 | CNR1 (0.49) | MTNR1AMTNR1BALDH1A1MAPTKDM4E | |
| SCHEMBL2860131 | 0.89 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL2857936 | 0.88 | KDM4E (0.47) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL2856697 | 0.87 | KDM4E (0.46) | ALDH1A1MAPTKDM4ESMN1; SMN2POLB | |
| SCHEMBL2850868 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2HTTHPGD | |
| SCHEMBL2854509 | 0.86 | KDM4E (0.50) | ALDH1A1MAPTKDM4ESMN1; SMN2POLB | |
| SCHEMBL2856750 | 0.85 | P2RX7 (0.42) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL2859429 | 0.85 | NPC1 (0.46) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL2852117 | 0.84 | P2RX7 (0.48) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL2848513 | 0.84 | P2RX7 (0.43) | ALDH1A1MAPTKDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |