Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6082196 | 0.85 | LMNA (0.51) | ALDH1A1MAPTLMNASMN1; SMN2RAB9A | |
| SCHEMBL1792783 | 0.81 | MAPT (0.58) | ALDH1A1MAPTRAB9AKMT2AMMP2 | |
| SCHEMBL27981545 | 0.81 | MAPT (0.58) | ALDH1A1MAPTRAB9AKMT2AMMP2 | |
| SCHEMBL1790581 | 0.79 | MAPT (0.58) | ALDH1A1MAPTLMNARAB9AKMT2A | |
| SCHEMBL1571372 | 0.79 | ALDH1A1 (0.68) | FAAHALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL12614112 | 0.79 | TRPA1 (0.55) | ALDH1A1MAPTRAB9AKMT2APOLB | |
| SCHEMBL31173291 | 0.79 | ALDH1A1 (0.71) | ALDH1A1MAPTLMNACA1CA2 | |
| SCHEMBL1792200 | 0.79 | ALDH1A1 (0.71) | ALDH1A1MAPTLMNACA1CA2 | |
| SCHEMBL28910686 | 0.78 | FAAH (0.48) | FAAHALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL1793733 | 0.78 | HSD11B1 (0.61) | ALDH1A1MAPTRAB9AKMT2AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112608269-B | Method for catalytically synthesizing pyrrolidine by weak interaction of chalcogen | 山东大学 | 2022-05-06 | — | — | CN | disclosed |
| WO-2021249475-A1 | FUSED QUINAZOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2021-12-16 | — | — | WO | disclosed |
| CN-112608269-A | Method for catalytically synthesizing pyrrolidine by weak interaction of chalcogen | 山东大学 | 2021-04-06 | — | — | CN | disclosed |