Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | DDT | P30046 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850550 | 0.92 | CCR1 (0.54) | CCR1KDM4EDDT | |
| SCHEMBL2854543 | 0.92 | CCR1 (0.54) | TP53CCR1DDTMAPTKMT2A | |
| SCHEMBL2861243 | 0.90 | KDM4E (0.52) | CCR1KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL2860247 | 0.89 | CCR1 (0.59) | CCR1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL2856304 | 0.89 | KEAP1 (0.53) | CCR1KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL2857598 | 0.89 | KMT2A (0.48) | KDM4EALDH1A1HPGDPOLBMAPT | |
| SCHEMBL2857073 | 0.85 | CCR1 (0.48) | CCR1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL2859307 | 0.84 | TSHR (0.46) | CCR1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL2854462 | 0.84 | KEAP1 (0.48) | CCR1KDM4EALDH1A1MAPTKEAP1 | |
| SCHEMBL2854847 | 0.84 | ALDH1A1 (0.48) | TP53CCR1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |