Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855796 | 0.88 | ALDH1A1 (0.43) | L3MBTL1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL2853241 | 0.85 | SMN1; SMN2 (0.41) | L3MBTL1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL2854992 | 0.85 | L3MBTL1 (0.43) | L3MBTL1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL2852553 | 0.82 | MALT1 (0.40) | L3MBTL1SMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL2854492 | 0.80 | MAPT (0.42) | L3MBTL1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL2853088 | 0.80 | NR3C1 (0.41) | L3MBTL1RAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL2856974 | 0.80 | MAPT (0.39) | L3MBTL1SMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL2852387 | 0.80 | P2RX7 (0.37) | RXFP1 | |
| SCHEMBL2850882 | 0.79 | MALT1 (0.44) | — | |
| SCHEMBL2859504 | 0.79 | TAAR1 (0.43) | RAB9ANPC1TSHRLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |