Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.39 |
| ▸ | NSD2 | O96028 | 3/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941302 | 0.75 | MEN1 (0.39) | TDP2PLCG1CES1MEN1THRB | |
| SCHEMBL25251959 | 0.74 | TDP2 (0.39) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL10434480 | 0.68 | TDP2 (0.49) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL607872 | 0.66 | TDP2 (0.37) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL28077985 | 0.64 | S100A4 (0.45) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL8905893 | 0.62 | IDO1 (0.33) | IDO1 | |
| SCHEMBL30168823 | 0.62 | IDO1 (0.33) | IDO1 | |
| SCHEMBL1749823 | 0.60 | GAA (0.50) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL25213079 | 0.58 | CCNA2 (0.37) | TDP2NSD2PAX8ABL1PLCG1 | |
| SCHEMBL2299734 | 0.58 | CCNA2 (0.40) | TDP2NSD2PAX8ABL1PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112334191-B | Pharmaceutically effective compounds for selectively inhibiting myosin 2 isoforms | 普林特商业服务有限公司 | 2024-12-10 | — | — | CN | claimed |
| CN-112334191-A | Pharmaceutically effective compounds for selective inhibition of myosin 2 isoforms | 普林特商业服务有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-112334191-B | Pharmaceutically effective compounds for selectively inhibiting myosin 2 isoforms | 普林特商业服务有限公司 | 2024-12-10 | — | — | CN | disclosed |
| US-20240270752-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | EÖTVÖS LORÁND TUDOMÁNYEGYETEM (HU) | 2024-08-15 | — | — | US | disclosed |
| CN-117924285-A | Pharmaceutically effective compounds for selectively inhibiting myosin 2 isoforms | 普林特商业服务有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-112334191-A | Pharmaceutically effective compounds for selective inhibition of myosin 2 isoforms | 普林特商业服务有限公司 | 2021-02-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240270752-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | MYH2, MYLK2, MYO1B | TDP2 205/4885NSD2 3333/4885PAX8 3249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.