Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 19/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL285399 | 0.87 | KIF11 (0.44) | KIF11POLBAPEX1HTTTDP1 | |
| SCHEMBL285289 | 0.87 | POLB (0.41) | KIF11POLBAPEX1HTTTDP1 | |
| SCHEMBL285742 | 0.85 | THRB (0.40) | KIF11POLBAPEX1HTTTDP1 | |
| SCHEMBL17253343 | 0.84 | KIF11 (0.54) | KIF11 | |
| SCHEMBL285750 | 0.82 | SCN1A (0.41) | KIF11POLBAPEX1HTTTDP1 | |
| SCHEMBL295983 | 0.79 | TDP1 (0.45) | KIF11POLBAPEX1HTTTDP1 | |
| SCHEMBL2392778 | 0.78 | MTNR1A (0.50) | POLBAPEX1HTTTDP1 | |
| SCHEMBL20695547 | 0.78 | KIF11 (0.55) | KIF11 | |
| SCHEMBL26011568 | 0.78 | KIF11 (0.49) | KIF11 | |
| SCHEMBL285400 | 0.78 | TDP1 (0.47) | KIF11POLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729203-B2 | Polymer composition | CONTAMAC LIMITED (GB) | 2014-05-20 | — | — | US | disclosed |
| EP-2427509-A1 | POLYMER COMPOSITION | Contamac Limited (GB) | 2012-03-14 | — | — | EP | disclosed |
| US-20120053313-A1 | POLYMER COMPOSITION | CONTAMAC LIMITED (GB) | 2012-03-01 | — | — | US | disclosed |
| WO-2010128266-A1 | POLYMER COMPOSITION | CONTAMAC LIMITED (GB) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053313-A1 | POLYMER COMPOSITION | UACA, CRYAA, CRYZ | KIF11 519/4885POLB 1398/4885APEX1 2086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.