Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308442 | 0.83 | KMT2A (0.41) | MEN1MAPTKMT2APAX8 | |
| SCHEMBL7446003 | 0.83 | KMT2A (0.41) | MEN1MAPTKMT2APAX8 | |
| SCHEMBL2861381 | 0.81 | XBP1 (0.37) | MEN1KMT2APAX8 | |
| SCHEMBL2855207 | 0.81 | ITGA4 (0.37) | MEN1MAPTKMT2ASMN1; SMN2PAX8 | |
| SCHEMBL8380101 | 0.80 | KMT2A (0.45) | MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7439074 | 0.80 | GPR119 (0.43) | HDAC1HDAC2HDAC3GPR119HDAC6 | |
| SCHEMBL2855171 | 0.79 | XDH (0.39) | HDAC1HDAC6KDM4EMEN1MAPT | |
| SCHEMBL7479568 | 0.78 | MT-CO2 (0.46) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL7479440 | 0.78 | MT-CO2 (0.46) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL8909415 | 0.78 | KMT2A (0.40) | HDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346971-B1 | Production method for biarylalanine | SUMITOMO CHEMICAL CO (JP) | 2010-01-20 | — | — | EP | disclosed |
| EP-1346971-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-24 | — | — | EP | disclosed |