Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSH | P09668 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11620783 | 0.81 | MAOA (0.41) | GRM2MAOAGAAMAPT | |
| SCHEMBL2233789 | 0.78 | MAOA (0.38) | GRM2MAOAGAAMAPT | |
| SCHEMBL2233413 | 0.66 | NPBWR1 (0.36) | ALOX5GRM2GAA | |
| SCHEMBL2236268 | 0.60 | MGLL (0.45) | MAPTLMNA | |
| SCHEMBL24776903 | 0.60 | MGLL (0.44) | MAOAGAADDB1CRBNLMNA | |
| SCHEMBL9230106 | 0.60 | CTSV (0.46) | ALOX5GRM2CTSVCTSLCTSB | |
| SCHEMBL7065588 | 0.58 | ALOX5 (0.42) | ALOX5MAOAGAAMAPTLMNA | |
| SCHEMBL8097128 | 0.58 | GAA (0.42) | ALOX5GAADDB1CRBNMAPT | |
| SCHEMBL7798882 | 0.58 | GAA (0.42) | ALOX5MAOAGAAMAPTLMNA | |
| SCHEMBL10335498 | 0.58 | GAA (0.46) | ALOX5CTSVCTSLCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238131-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - Portela & Ca., S.A. (PT) | 2010-10-13 | — | — | EP | claimed |
| WO-2009084970-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL-PORTELA & COMPANHIA, S.A. (PT) | 2009-07-09 | — | — | WO | claimed |
| US-4076824-A | Anthelmintic oxadiazolinone derivatives | RHONE-POULENC INDUSTRIES (FR) | 1978-02-28 | — | — | US | disclosed |