Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 13/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MST1R | Q04912 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853326 | 0.85 | MALT1 (0.39) | MALT1KDM4EALDH1A1METAXL | |
| SCHEMBL2855927 | 0.83 | MALT1 (0.57) | MALT1 | |
| SCHEMBL2852442 | 0.82 | MALT1 (0.56) | MALT1 | |
| SCHEMBL2855599 | 0.79 | MALT1 (0.57) | MALT1 | |
| SCHEMBL2849153 | 0.78 | MAPT (0.56) | MALT1KDM4EALDH1A1METAXL | |
| SCHEMBL2855560 | 0.76 | ALDH1A1 (0.49) | KDM4EALDH1A1METAXLMAPT | |
| SCHEMBL2856196 | 0.74 | MAPT (0.70) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2852073 | 0.71 | MAPT (0.71) | KDM4EALDH1A1METAXLMAPT | |
| SCHEMBL2857721 | 0.70 | ALDH1A1 (0.52) | KDM4EALDH1A1METAXLMAPT | |
| SCHEMBL2855562 | 0.70 | MAPT (0.46) | KDM4EALDH1A1METAXLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |