SCHEMBL285580

SCHEMBL285580

CC=[Zr](C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.34
HTR6 P50406 1/20 0.34
SIGMAR1 Q99720 6/20 0.32
KDM4E B2RXH2 2/20 0.32
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
CHRM3 P20309 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL19874877 0.98 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
Hydrochloric Acid SCHEMBL19874835 0.98 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL8857293 0.87 GPR3 (0.31) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL8382871 0.80 SIGMAR1 (0.37) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL29758162 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL6763868 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL2136144 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL6440197 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL15863401 0.77 HTR2A (0.40) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL8167362 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1597632-B1 NON-MAGNETIC MONOCOMPONENT POSITIVE TONER COMPOSITION HAVING SUPERIOR TRANSFER EFFICIENCY LG CHEMICAL LTD (KR) 2013-03-27 EP claimed
EP-1799726-B1 TRIALKYLALUMINUM TREATED SUPPORTS EXXONMOBIL CHEM PATENTS INC (US) 2011-07-13 EP claimed
WO-2004026923-A9 SUPERCRITICAL POLYMERIZATION PROCESS AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEM PATENTS INC (US) 2004-09-10 WO claimed
EP-1090047-B1 POLYMERIZATIONS USING ADJUVANT CATALYST HUNTSMAN POLYMERS CORP (US) 2004-08-04 EP claimed
EP-0834514-B1 Process for synthesizing metallocene compounds KANTO KAGAKU (JP) 2003-10-22 EP claimed
EP-1311558-A1 METHOD FOR PRODUCING HIGHLY PRODUCTIVE SUPPORTED IONIC CATALYST FOR GAS PHASE POLYMERIZATION Univation Technologies LLC (US) 2003-05-21 EP claimed
WO-2002010227-A1 METHOD FOR PRODUCING HIGHLY PRODUCTIVE SUPPORTED IONIC CATALYST FOR GAS PHASE POLYMERIZATION UNIVATION TECHNOLOGIES, LLC (US) 2002-02-07 WO claimed
EP-0789624-B1 PROCESS FOR PRODUCING BIOMODAL MOLECULAR WEIGHT DISTRIBUTION ETHYLENE POLYMERS AND COPOLYMERS MOBIL OIL CORP (US) 2000-03-22 EP claimed
EP-0523416-B1 Catalyst and process for preparing high molecular weight polyolefines TARGOR GMBH (DE) 1999-10-20 EP claimed
EP-0366290-B1 Process for producing olefin polymers CHISSO CORP (JP) 1994-06-29 EP claimed
US-20230137384-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. 2023-05-04 US disclosed
US-11618791-B2 Systems and methods for producing a supported catalyst EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-04-04 US disclosed
EP-2894176-B1 Catalyst composition comprising shuttling agent for regio-irregular multi-block copolymer formation DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-01 EP disclosed
US-20210283172-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. 2021-09-16 US disclosed
WO-2021108049-A1 SYSTEMS AND METHODS FOR PRODUCING A SUPPORTED CATALYST EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-06-03 WO disclosed
EP-0287666-A1 PROCESS FOR POLYMERIZING OLEFINS Mitsui Chemicals, Inc. (JP) 1988-10-26 EP disclosed
EP-0285443-A1 Process for producing solid catalyst for polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-10-05 EP disclosed
EP-0283164-A2 Cyclo-olefinic random copolymer, olefinic random copolymer, and process for producing cyclo-olefinic random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-21 EP disclosed
EP-0279863-A1 CATALYST FOR POLYMERIZING ALPHA-OLEFIN AND POLYMERIZATION PROCESS MITSUI CHEMICALS, INC. (JP) 1988-08-31 EP disclosed
EP-0279586-A2 Finely divided aluminoxane, process for producing same and its use MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-08-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210283172-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY OGFR, ALOX5, PTGS1 HTR2A 2553/4885HTR6 2080/4885SIGMAR1 151/4885
US-20230137384-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY OGFR, ALOX5, PTGS1 HTR2A 2553/4885HTR6 2080/4885SIGMAR1 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.