Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | HBB | P68871 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31020712 | 0.88 | ADORA2A (0.56) | ADORA2AADORA2BLMNAADORA3ADORA1 | |
| SCHEMBL29093038 | 0.87 | IMPDH2 (0.61) | ADORA1 | |
| SCHEMBL873210 | 0.86 | LMNA (0.58) | ADORA2AADORA2BGMNNALDH1A1LMNA | |
| SCHEMBL1979500 | 0.86 | LMNA (0.58) | ADORA2AADORA2BGMNNALDH1A1LMNA | |
| SCHEMBL23414481 | 0.85 | LMNA (0.59) | ADORA2AADORA2BGMNNALDH1A1LMNA | |
| SCHEMBL30852235 | 0.85 | LMNA (0.59) | ADORA2AADORA2BGMNNALDH1A1LMNA | |
| SCHEMBL29092957 | 0.84 | P2RY1 (0.61) | ALDH1A1 | |
| SCHEMBL8185399 | 0.84 | LMNA (0.58) | ADORA2AADORA2BGMNNALDH1A1LMNA | |
| SCHEMBL8185392 | 0.84 | LMNA (0.58) | ADORA2AADORA2BGMNNALDH1A1LMNA | |
| SCHEMBL21544852 | 0.84 | LMNA (0.58) | ADORA2AADORA2BGMNNALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116716367-A | Method for synthesizing 3' -methoxy guanosine diphosphate by multienzyme cascade reaction and application thereof | 武汉糖智药业有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-112661802-B | Synthetic method of 3' -methoxyguanosine | 阿里生物新材料（常州）有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-112661802-A | Synthetic method of 3' -methoxyguanosine | 阿里生物新材料（常州）有限公司 | 2021-04-16 | — | — | CN | disclosed |