Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.36 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2862996 | 0.89 | CCNE1 (0.38) | CHRNA7HRH3BTKACKR3CCNE1 | |
| SCHEMBL974821 | 0.87 | HRH3 (0.38) | CHRNA7PAK1HRH3BTKDPP4 | |
| SCHEMBL2856121 | 0.84 | PAK1 (0.40) | CHRNA7PAK1HRH3BTKDPP4 | |
| SCHEMBL2863170 | 0.84 | PPARG (0.36) | PAK1BTKKARS1DPP4SMPD3 | |
| SCHEMBL2854222 | 0.82 | SMN1; SMN2 (0.40) | PAK1HRH3BTKKARS1DPP4 | |
| SCHEMBL973764 | 0.81 | BTK (0.45) | CHRNA7HRH3BTKDPP4ACKR3 | |
| SCHEMBL973812 | 0.80 | HRH3 (0.38) | CHRNA7HRH3BTKDPP4ACKR3 | |
| SCHEMBL975864 | 0.80 | BTK (0.38) | CHRNA7HRH3BTKACKR3SMPD3 | |
| SCHEMBL2853786 | 0.80 | LMNA (0.38) | PAK1BTKACKR3KMT2A | |
| SCHEMBL974669 | 0.79 | HRH3 (0.39) | CHRNA7HRH3BTKACKR3SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968957-B1 | SUBSTITUTED THIAZOLES AND THEIR USE FOR PRODUCING DRUGS | GRUENENTHAL GMBH (DE) | 2010-01-20 | — | — | EP | claimed |