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SCHEMBL2856321

SCHEMBL2856321

C/C=C(/C(=O)O)c1ccccc1Oc1cccc(OC(C)C)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.44
▸ POLB P06746 1/20 0.44
▸ CTNNB1 P35222 1/20 0.43
▸ ALDH1A1 P00352 2/20 0.42
▸ NSD2 O96028 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ IRAK4 Q9NWZ3 2/20 0.42
▸ RXRA P19793 1/20 0.41
▸ RXRB P28702 1/20 0.41
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ MTNR1B P49286 1/20 0.40
▸ HTR1D P28221 1/20 0.40
▸ HTR1B P28222 1/20 0.40
▸ PTGS1 P23219 1/20 0.40
▸ SIRT1 Q96EB6 1/20 0.39
▸ MAPT P10636 2/20 0.39
▸ HTT P42858 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2107687 1.00 KDM4E (0.44) KDM4EPOLBCTNNB1ALDH1A1NSD2
SCHEMBL2856319 0.89 KDM4E (0.44) KDM4EPOLBCTNNB1ALDH1A1NSD2
SCHEMBL30051492 0.89 KDM4E (0.44) KDM4EPOLBCTNNB1ALDH1A1NSD2
SCHEMBL2107684 0.89 KDM4E (0.44) KDM4EPOLBCTNNB1ALDH1A1NSD2
SCHEMBL2107689 0.89 KDM4E (0.44) KDM4EPOLBCTNNB1ALDH1A1NSD2
SCHEMBL2107594 0.86 KDM4E (0.59) KDM4EPOLBCTNNB1ALDH1A1MEN1
SCHEMBL2855939 0.86 KDM4E (0.59) KDM4EPOLBCTNNB1ALDH1A1MEN1
SCHEMBL2657444 0.85 KDM4E (0.56) KDM4EPOLBCTNNB1ALDH1A1NSD2
SCHEMBL2106716 0.84 CTNNB1 (0.59) POLBCTNNB1ALDH1A1SMN1; SMN2MEN1
SCHEMBL2847810 0.84 CTNNB1 (0.59) POLBCTNNB1ALDH1A1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043600-B2 Microbiocidal compounds SYNGENTA CROP PROTECTION AG (CH) 2024-07-23 — — US disclosed
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-06-18 — — US disclosed
US-11882834-B2 Microbiocidal thiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-01-30 — — US disclosed
EP-4271185-A1 DELIVERY SYSTEM FOR PLANT PROTECTION Omya International AG (CH) 2023-11-08 — — EP disclosed
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide SYNGENTA PARTICIPATIONS AG (CH) 2023-09-05 — — US disclosed
EP-3717479-B1 MICROBIOCIDAL THIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2023-07-05 — — EP disclosed
EP-3941898-B1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-06-07 — — EP disclosed
US-11629129-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-04-18 — — US disclosed
US-11629138-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-04-18 — — US disclosed
EP-3692029-B1 MICROBIOCIDAL PICOLINAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2023-04-12 — — EP disclosed
US-6893651-B1 Synergistic combination of cyclic ketoenol with agonists or antagonists of nicotinic acetylcholine receptors; protecting plants BAYER AKTIENGESELLSCHAFT (DE) 2005-05-17 — — US disclosed
US-6846777-B2 Synergistic biocidal composition THOR GMBH (DE) 2005-01-25 — — US disclosed
US-20040127520-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2004-07-01 — — US disclosed
US-6686387-B2 SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS; PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2004-02-03 — — US disclosed
US-20030199490-A1 Synergistic biocidal composition THOR GMBH (DE) 2003-10-23 — — US disclosed
US-20030092641-A1 Synergistic insecticidal mixtures DOW AGROSCIENCES LLC 2003-05-15 — — US disclosed
US-6444667-B1 OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2002-09-03 — — US disclosed
US-5622546-A Mould-resistant emulsion paints BAYER AKTIENGESELLSCHAFT (DE) 1997-04-22 — — US disclosed
WO-1997001547-A1 BENZAZOLE DERIVATIVES WITH MICROBIOCIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 1997-01-16 — — WO disclosed
US-5466693-A FOE USE IN THE CULTIVATION OF RICE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092641-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 KDM4E 3852/4885POLB 4880/4885CTNNB1 3858/4885
US-12043600-B2 Microbiocidal compounds MPO, MSR1, PRF1 KDM4E 2462/4885POLB 3401/4885CTNNB1 4410/4885
US-20040127520-A1 Synergistic insecticidal mixtures CHRM3, ACHE, CHRM2 KDM4E 3852/4885POLB 4880/4885CTNNB1 3858/4885
US-11882834-B2 Microbiocidal thiazole derivatives MSR1, TLR1, IFNG KDM4E 3260/4885POLB 3655/4885CTNNB1 4135/4885
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives TLR1, TLR5, IDO1 KDM4E 2885/4885POLB 2340/4885CTNNB1 2621/4885
US-11629138-B2 Microbiocidal picolinamide derivatives PRF1, CASP1, FPR1 KDM4E 2969/4885POLB 3534/4885CTNNB1 4630/4885
US-11744246-B2 Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide PHF20, FUCA1, ZP1 KDM4E 4050/4885POLB 4375/4885CTNNB1 4851/4885
US-11629129-B2 Microbiocidal picolinamide derivatives PRF1, CASP1, MSR1 KDM4E 3192/4885POLB 3215/4885CTNNB1 4671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.