SCHEMBL28564294

SCHEMBL28564294

Nc1ncc(F)cc1COC=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 1/20 0.33
ALK Q9UM73 1/20 0.32
SRC P12931 1/20 0.31
ALDH1A1 P00352 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28288412 0.80 KMT2A (0.44) MAP4K4ALKSRCALDH1A1
SCHEMBL2123145 0.77 LMNA (0.47) ALKALDH1A1
SCHEMBL2125142 0.74 NOS3 (0.42)
SCHEMBL21722371 0.72 LOXL2 (0.36)
SCHEMBL2121398 0.71 MAP4K4 (0.34) MAP4K4
SCHEMBL27906402 0.71 APLNR (0.40) ALDH1A1L3MBTL1
SCHEMBL2120520 0.70 BACE1 (0.33) ALK
SCHEMBL28108882 0.69
SCHEMBL27886427 0.69 LTA4H (0.41) SRCALDH1A1
SCHEMBL15544922 0.68 MMP2 (0.42) SRCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107903209-B Synthetic method of 2-amino-5-fluoropyridine-3-methyl formate 宁夏忠同生物科技有限公司 2021-05-14 CN claimed
CN-107903209-B Synthetic method of 2-amino-5-fluoropyridine-3-methyl formate 宁夏忠同生物科技有限公司 2021-05-14 CN disclosed
CN-107903209-B Synthetic method of 2-amino-5-fluoropyridine-3-methyl formate 宁夏忠同生物科技有限公司 2021-05-14 CN disclosed
CN-107903209-B Synthetic method of 2-amino-5-fluoropyridine-3-methyl formate 宁夏忠同生物科技有限公司 2021-05-14 CN disclosed