SCHEMBL2856574

SCHEMBL2856574

CC(C)C(C)(C)NC(=O)c1ccnc(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 2/20 0.47
TAS1R1 Q7RTX1 2/20 0.47
TAS1R2 Q8TE23 2/20 0.47
ANO1 Q5XXA6 2/20 0.44
PREP P48147 1/20 0.43
FAP Q12884 1/20 0.43
LMNA P02545 3/20 0.41
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
GRM5 P41594 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
AAK1 Q2M2I8 1/20 0.39
SMARCA2 P51531 2/20 0.38
SMARCA4 P51532 2/20 0.38
SLC6A3 Q01959 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13701663 0.84 TAS1R3 (0.51) TAS1R3TAS1R1TAS1R2ANO1LMNA
SCHEMBL2861520 0.80 KCNK3 (0.50) ANO1LMNAMEN1MAPK1KMT2A
SCHEMBL2865570 0.79 PREP (0.48) TAS1R3TAS1R1TAS1R2PREPFAP
SCHEMBL2801067 0.78 FDPS (0.57) TAS1R3TAS1R1TAS1R2PREPFAP
SCHEMBL5743063 0.76 TAS1R3 (0.55) TAS1R3TAS1R1TAS1R2PREPFAP
SCHEMBL24568629 0.76 PREP (0.50) TAS1R3TAS1R1TAS1R2PREPFAP
SCHEMBL2856039 0.76 PREP (0.50) TAS1R3TAS1R1TAS1R2PREPFAP
SCHEMBL2856403 0.76 PREP (0.50) TAS1R3TAS1R1TAS1R2PREPFAP
SCHEMBL10705725 0.75 HPGD (0.53) TAS1R3TAS1R1TAS1R2PREPFAP
SCHEMBL24571395 0.73 ALDH1A1 (0.53) TAS1R3TAS1R1TAS1R2ANO1PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137376-A1 AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20100137376-A1 AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
EP-2174931-A1 AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME Sumitomo Chemical Company, Limited (JP) 2010-04-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137376-A1 AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME NAAA, NAT1, SAT1 TAS1R3 4053/4885TAS1R1 3002/4885TAS1R2 3382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.