Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | MST1R | Q04912 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860020 | 0.86 | KDM4E (0.51) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL2859050 | 0.85 | PTGS1 (0.46) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL2859651 | 0.85 | MAPT (0.46) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL2859508 | 0.82 | CYP1A2 (0.46) | MAPTALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL2856759 | 0.81 | ACLY (0.44) | ATMMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL2852552 | 0.81 | MEN1 (0.51) | MAPTALDH1A1KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL2855775 | 0.81 | P2RY1 (0.44) | ATMMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL2848541 | 0.80 | RAB9A (0.43) | MAPTALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL2854596 | 0.80 | TP53 (0.46) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL2860986 | 0.80 | MAPT (0.45) | MAPTALDH1A1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |