Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142657 | 0.90 | NPC1 (0.75) | HPGDNPC1USP2ALDH1A1RAB9A | |
| SCHEMBL23080160 | 0.87 | MTNR1B (0.70) | HPGDNPC1USP2ALDH1A1RAB9A | |
| SCHEMBL5806693 | 0.87 | HPGD (0.68) | HPGDNPC1USP2ALDH1A1RAB9A | |
| SCHEMBL1141400 | 0.87 | MTNR1B (0.81) | HPGDNPC1USP2ALDH1A1RAB9A | |
| SCHEMBL16896918 | 0.85 | NPC1 (0.74) | HPGDNPC1USP2ALDH1A1RAB9A | |
| SCHEMBL31390722 | 0.85 | ALDH1A1 (0.70) | HPGDNPC1USP2ALDH1A1RAB9A | |
| SCHEMBL3753125 | 0.85 | HPGD (0.67) | HPGDNPC1USP2ALDH1A1RAB9A | |
| SCHEMBL3470179 | 0.85 | MEN1 (0.69) | HPGDNPC1USP2ALDH1A1RAB9A | |
| SCHEMBL2502606 | 0.85 | NPC1 (0.76) | HPGDNPC1USP2ALDH1A1RAB9A | |
| SCHEMBL30619848 | 0.85 | HPGD (0.67) | HPGDNPC1USP2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070016-A1 | Method and composition for increasing reproduction in mammalian and avian species | THE UNIVERSITY OF UTAH (US) | 1983-01-19 | — | — | EP | claimed |
| CN-1984900-B | Indole derivatives having piperidine ring | EISAI R&D MAN CO LTD | 2010-11-10 | — | — | CN | disclosed |
| US-7794761-B2 | Methods for inducing anti-anxiety and calming effects in animals and humans | SEROCTIN RESEARCH & TECHNOLOGY, INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-7521468-B2 | Compounds for use in weight loss and appetite suppression in humans | SEROCTIN RESEARCH & TECHNOLOGY, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| CN-1984900-A | Indole derivatives having piperidine ring | EISAI R&D MAN CO LTD (JP) | 2007-06-20 | — | — | CN | disclosed |
| EP-1765338-A1 | METHODS FOR INDUCING ANTI-ANXIETY AND CALMING EFFECTS IN ANIMALS AND HUMANS | Seroctin Research & Technologies, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| US-20060223796-A1 | Novel compounds for use in weight loss and appetite suppression in humans | SAVANNA HEALTH LLC | 2006-10-05 | — | — | US | disclosed |
| WO-2006017281-A1 | METHODS FOR INDUCING ANTI-ANXIETY AND CALMING EFFECTS IN ANIMALS AND HUMANS | SEROCTIN RESEARCH & TECHNOLOGY, INC. (US) | 2006-02-16 | — | — | WO | disclosed |
| US-20050250772-A1 | Methods for inducing anti-anxiety and calming effects in animals and humans | SAVANNA HEALTH LLC | 2005-11-10 | — | — | US | disclosed |
| US-20040209877-A1 | Methods for augmenting immune defenses contemplating the administration of phenolic and indoleamine-like compounds for use in animals ans humans | SEROCTIN RESEARCH & TECHNOLOGY, INC. | 2004-10-21 | — | — | US | disclosed |
| US-20040192669-A1 | Novel compounds for use in weight loss and appetite suppression in humans | SEROCTIN RESEARCH & TECHNOLOGY, INC. | 2004-09-30 | — | — | US | disclosed |
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5081121-A | Cardiotonic agents | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0343574-A1 | 4(1H)-quinolone derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |
| EP-0070016-A1 | Method and composition for increasing reproduction in mammalian and avian species | THE UNIVERSITY OF UTAH (US) | 1983-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192669-A1 | Novel compounds for use in weight loss and appetite suppression in humans | CPT1B, FABP4, EGLN1 | HPGD 388/4885NPC1 2135/4885USP2 3891/4885 |
| US-20040209877-A1 | Methods for augmenting immune defenses contemplating the administration of phenolic and indoleamine-like compounds for use in animals ans humans | HAAO, HMOX1, IDO1 | HPGD 71/4885NPC1 3130/4885USP2 2345/4885 |
| US-20050250772-A1 | Methods for inducing anti-anxiety and calming effects in animals and humans | CALM1, HAAO, MYB | HPGD 72/4885NPC1 3756/4885USP2 4083/4885 |
| US-20060223796-A1 | Novel compounds for use in weight loss and appetite suppression in humans | CPT1B, EGLN3, MYB | HPGD 381/4885NPC1 2243/4885USP2 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.