Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.38 |
| ▸ | CA2 | P00918 | 12/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | MMP8 | P22894 | 3/20 | 0.35 |
| ▸ | MMP13 | P45452 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606069 | 0.78 | CA2 (0.44) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL384050 | 0.77 | HSD11B1 (0.47) | CA1CA2HSD11B1ALDH1A1HSD17B3 | |
| SCHEMBL3139776 | 0.77 | HSD11B1 (0.47) | CA1CA2HSD11B1ALDH1A1HSD17B3 | |
| SCHEMBL384931 | 0.76 | HSD11B1 (0.46) | CA1CA2HSD11B1ALDH1A1HSD17B3 | |
| SCHEMBL3137403 | 0.76 | HSD11B1 (0.46) | CA1CA2HSD11B1ALDH1A1HSD17B3 | |
| SCHEMBL3135789 | 0.76 | HSD11B1 (0.46) | CA1CA2HSD11B1ALDH1A1HSD17B3 | |
| SCHEMBL3135858 | 0.76 | HSD11B1 (0.46) | CA1CA2HSD11B1ALDH1A1HSD17B3 | |
| SCHEMBL1760784 | 0.76 | CA2 (0.48) | CA1CA2MMP1MMP2MMP9 | |
| Tert-Butylbenzene SCHEMBL5187676 | 0.75 | HSD11B1 (0.38) | CA1CA2MMP1MMP2MMP9 | |
| Diphenylsulfane SCHEMBL2897548 | 0.75 | CA1 (0.43) | CA1CA2CA9HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107073177-B | Single-component hydrophilic lubricating coating | 波士顿科学国际有限公司 | 2021-04-16 | — | — | CN | disclosed |