Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857946 | 0.87 | CNR1 (0.50) | CNR1HTR2AHTR2CMAPTMEN1 | |
| SCHEMBL2857729 | 0.86 | CNR1 (0.53) | CNR1CYP1A2HTR2AHTR2CMAPT | |
| SCHEMBL2850258 | 0.85 | MAPT (0.51) | CYP1A2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2852516 | 0.85 | MALT1 (0.39) | CNR1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2848317 | 0.84 | MAPT (0.46) | MAPTMEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL2860939 | 0.84 | LMNA (0.45) | CYP1A2MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL2854221 | 0.84 | MAPT (0.51) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL2852565 | 0.84 | MAPT (0.42) | CNR1CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL2854572 | 0.84 | RAB9A (0.44) | CYP1A2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2860829 | 0.83 | TNKS (0.42) | MAPTMEN1KMT2AKDM4EHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |