Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RHOC | P08134 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 3/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856756 | 0.93 | ACHE (0.40) | ACHEMAPTMEN1KMT2ARHOC | |
| SCHEMBL2860939 | 0.91 | LMNA (0.45) | MAPTMEN1KMT2ARHOCRHOA | |
| SCHEMBL2853385 | 0.90 | MAPT (0.42) | ACHEMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL2850258 | 0.89 | MAPT (0.51) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL2852360 | 0.89 | MAPT (0.42) | ACHEMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL2854221 | 0.87 | MAPT (0.51) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL2854572 | 0.87 | RAB9A (0.44) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL2852565 | 0.87 | MAPT (0.42) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL2853258 | 0.87 | NPY5R (0.45) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL2848615 | 0.87 | MAPT (0.44) | MAPTMEN1KMT2ANPSR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |