Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2862045 | 0.83 | ABCC8 (0.50) | KMT2AALDH1A1RAB9AABCC8KCNJ11 | |
| SCHEMBL574894 | 0.81 | L3MBTL1 (0.42) | MEN1KMT2AL3MBTL1MMP1MMP2 | |
| SCHEMBL2869701 | 0.79 | MMP1 (0.46) | L3MBTL1MMP1MMP2MMP9MMP12 | |
| SCHEMBL14964147 | 0.76 | NAAA (0.40) | MEN1KMT2AL3MBTL1MMP1MMP2 | |
| SCHEMBL2873389 | 0.74 | ALDH1A1 (0.48) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL2866383 | 0.73 | SMN1; SMN2 (0.47) | MEN1KMT2APKMMAPTALDH1A1 | |
| SCHEMBL12852318 | 0.71 | ATM (0.58) | MEN1KMT2AALDH1A1HTTABCC8 | |
| SCHEMBL14213885 | 0.70 | ATM (0.48) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL14936915 | 0.69 | HPGD (0.62) | CASP3SENP8SENP7SENP6MEN1 | |
| SCHEMBL2859816 | 0.68 | MAPK1 (0.48) | L3MBTL1MAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852428-B1 | 4-CYCLOPROPYL-1,2,3-THIADIAZOLE COMPOUND, AGROHORTICULTURAL PLANT DISEASE CONTROLLING AGENT AND METHOD OF USING THE SAME | NIHON NOHYAKU CO LTD (JP) | 2012-05-16 | — | — | EP | claimed |
| US-7786040-B2 | 4-cyclopropyl-1,2,3,-thiadiazole compound, agrohorticultural plant disease controlling agent and method of using the same | NIHON NOHYAKU CO., LTD. (JP) | 2010-08-31 | — | — | US | claimed |
| WO-2010025870-A1 | SYNERGISTIC COMBINATIONS OF THIADIAZOL CARBONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | claimed |
| US-20080200457-A1 | 4-Cyclopropyl-1,2,3,-Thiadiazole Compound, Agrohorticultural Plant Disease Controlling Agent And Method Of Using The Same | NIHON NOHYAKU CO., LTD. (JP) | 2008-08-21 | — | — | US | claimed |
| EP-1852428-A1 | 4-CYCLOPROPYL-1,2,3-THIADIAZOLE COMPOUND, AGROHORTICULTURAL PLANT DISEASE CONTROLLING AGENT AND METHOD OF USING THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2007-11-07 | — | — | EP | claimed |
| EP-1852428-B1 | 4-CYCLOPROPYL-1,2,3-THIADIAZOLE COMPOUND, AGROHORTICULTURAL PLANT DISEASE CONTROLLING AGENT AND METHOD OF USING THE SAME | NIHON NOHYAKU CO LTD (JP) | 2012-05-16 | — | — | EP | disclosed |
| US-7786040-B2 | 4-cyclopropyl-1,2,3,-thiadiazole compound, agrohorticultural plant disease controlling agent and method of using the same | NIHON NOHYAKU CO., LTD. (JP) | 2010-08-31 | — | — | US | disclosed |
| WO-2010025870-A1 | SYNERGISTIC COMBINATIONS OF THIADIAZOL CARBONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |
| US-20080200457-A1 | 4-Cyclopropyl-1,2,3,-Thiadiazole Compound, Agrohorticultural Plant Disease Controlling Agent And Method Of Using The Same | NIHON NOHYAKU CO., LTD. (JP) | 2008-08-21 | — | — | US | disclosed |
| EP-1852428-A1 | 4-CYCLOPROPYL-1,2,3-THIADIAZOLE COMPOUND, AGROHORTICULTURAL PLANT DISEASE CONTROLLING AGENT AND METHOD OF USING THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2007-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200457-A1 | 4-Cyclopropyl-1,2,3,-Thiadiazole Compound, Agrohorticultural Plant Disease Controlling Agent And Method Of Using The Same | CBR3, CBR1, OSR1 | CASP3 313/4885SENP8 3205/4885SENP7 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.