SCHEMBL14964147

SCHEMBL14964147

Cc1ccc(COC(=O)c2snnc2C2CC2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.40
POLB P06746 1/20 0.40
MMP2 P08253 2/20 0.40
MMP12 P39900 2/20 0.40
MMP1 P03956 1/20 0.40
MMP9 P14780 1/20 0.40
ABCC8 Q09428 1/20 0.39
KCNJ11 Q14654 1/20 0.39
GPBAR1 Q8TDU6 1/20 0.38
TP53 P04637 2/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
LMNA P02545 1/20 0.38
GRIN2B Q13224 3/20 0.38
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
NPY1R P25929 1/20 0.37
MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574894 0.88 L3MBTL1 (0.42) MMP2MMP12MMP1MMP9ABCC8
SCHEMBL2862045 0.87 ABCC8 (0.50) POLBABCC8KCNJ11SMN1; SMN2KMT2A
SCHEMBL2866383 0.87 SMN1; SMN2 (0.47) ABCC8KCNJ11SMN1; SMN2MEN1KMT2A
SCHEMBL2873389 0.81 ALDH1A1 (0.48) POLBABCC8KCNJ11TP53SMN1; SMN2
SCHEMBL2869701 0.79 MMP1 (0.46) MMP2MMP12MMP1MMP9ABCC8
SCHEMBL2857375 0.76 CASP3 (0.48) POLBMMP2MMP12MMP1MMP9
SCHEMBL2859816 0.72 MAPK1 (0.48) NAAAPOLBTP53LMNAALDH1A1
SCHEMBL11535110 0.71 MAPT (0.64) POLBSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL18924216 0.70 TSHR (0.56) POLBABCC8KCNJ11SMN1; SMN2MEN1
SCHEMBL10335263 0.68 HTT (0.49) POLBSMN1; SMN2LMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130130898-A1 Fungicidal Compositions BASF SE (DE) 2013-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130130898-A1 Fungicidal Compositions CYP4X1, P2RX2, FLAD1 NAAA 516/4885POLB 2944/4885MMP2 1335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.