Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831007 | 0.83 | ALDH1A1 (0.46) | NR3C2ALDH1A1KMT2ARAB9AKDM5A | |
| SCHEMBL17436825 | 0.75 | CDK8 (0.60) | ALDH1A1CDK8CYP2C9 | |
| SCHEMBL23141464 | 0.74 | SMN1; SMN2 (0.39) | ALDH1A1KMT2ARAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1456373 | 0.74 | RAB9A (0.56) | ALDH1A1KMT2ARAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28941561 | 0.74 | MAPT (0.46) | ALDH1A1KMT2ARAB9AKDM5AKDM4C | |
| SCHEMBL18256262 | 0.73 | NPBWR1 (0.45) | ALDH1A1KMT2ARAB9AKDM5AKDM2B | |
| SCHEMBL18256245 | 0.71 | KDM5A (0.49) | ALDH1A1KMT2ARAB9AKDM5AKDM2B | |
| SCHEMBL9683620 | 0.71 | TDP1 (0.46) | NR3C2ALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL3417583 | 0.70 | POLB (0.50) | NR3C2KMT2ARAB9AKDM5AKDM4C | |
| SCHEMBL11128539 | 0.70 | KMT2A (0.35) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573914-B | Pyrazolyl-ureas as kinase inhibitors | 瑞斯比维特有限公司 | 2021-05-28 | — | — | CN | disclosed |