Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854763 | 0.95 | DRD4 (0.50) | SIGMAR1 | |
| SCHEMBL2859595 | 0.86 | CHRM4 (0.53) | CHRM4 | |
| SCHEMBL2863246 | 0.82 | DRD4 (0.49) | SIGMAR1 | |
| SCHEMBL2856452 | 0.81 | DRD4 (0.47) | SIGMAR1SLC6A12 | |
| SCHEMBL2857980 | 0.80 | DRD4 (0.47) | SIGMAR1CHRM4 | |
| SCHEMBL2853388 | 0.80 | CCR1 (0.48) | — | |
| SCHEMBL2855547 | 0.79 | TAAR1 (0.54) | — | |
| SCHEMBL2852970 | 0.78 | DRD2 (0.51) | SIGMAR1 | |
| SCHEMBL2856213 | 0.78 | CNR1 (0.47) | — | |
| SCHEMBL2848317 | 0.77 | MAPT (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |